Butabarbital decreases results of sufentanil SL by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Intently. Coadministration of CYP3A4 inducers might lessen sufentanil degrees and efficacy, perhaps precipitating withdrawal syndrome in patients which have made Actual physical dependence to sufentanil. Discontinuation of concomitantly employed CYP3A4 inducer... https://paulh654vdj4.oblogation.com/profile