The coronavirus papain-like protease (PLpro) is crucial for viral replicase polyprotein processing. Additionally. PLpro can subvert host defense mechanisms by its deubiquitinating (DUB) and deISGylating activities. To elucidate the role of these activities during SARS-CoV-2 infection. https://www.chiggate.com/shades-eq-09gi-hamptons-supply/