So as to rationalise the observed ABL kinase inhibitory outcomes from the 3D structural point of view, the lead compounds I and II, along with the newly designed derivatives 4a, 4b, and five had been docked inside the catalytic kinase domains of BCR-ABLWT (PDB code: 3OXZ) and BCR-ABLT315I (PDB code: https://franciscozshxl.blog2freedom.com/31073765/indazole-structure-an-overview