The activation of CB1 and CB2 inhibits the formation of intracellular cAMP, that's why bringing about a tremendous reduction on the excitatory effect within the neurons [88,89]. In addition, the activation of CB2 can even more prevent the mast cell degranulation and the discharge of pro-inflammatory mediators, creating the https://keeganovofv.digiblogbox.com/52305938/the-best-side-of-block-pain-receptors-with-proleviate